Esodeviation is comitant in all fields of . [3], from 945 patients complaining of double vision, majority of patients between 60 and 80 years, approx 31% had SES and were older, ~71 years old, with ~60% female predominance. Educating patients on the benefits of prism wear is key in helping get them on board in these cases. It is reasonable to initially defer further investigation, including neuroimaging, in patients who have no other neurologic symptoms or signs. Convergence insufficiency is a common eye coordination problem in which the eyes drift outward when reading or doing near point work. As her vision improved with amblyopia treatment, I continued to monitor her sensory fusion. Parkinson disease 4. Common symptoms include: headaches; blurred vision ; double vision Divergence Insufficiency Revisited: Natural History of Idiopathic Cases and Neurologic Associations | Neurology | JAMA Ophthalmology | JAMA Network ObjectivesTo determine the natural history of primary divergence insufficiency and to identify clinical features that distinguish patients with this neurologica [Skip to Navigation] 127. Methods 6. What is divergence insufficiency? NADivergence paralysis. Her cover test revealed a 25 PD constant right esotropia with a 2 PD constant right hypotropia. 1994, Philadelphia, PA: Lippincott Williams & Wilkins. In addition, all patients underwent examination of ocular motility using a Maddox rod to demonstrate that the angle of uncrossed deviation increased as the viewing distance increased, remained the same or decreased in right and left gazes at distance, and decreased as the viewing distance decreased. Fusion prism is the minimum amount of prism needed to see a change from diplopia or suppression to normal binocular vision.12 To determine prism using this method, use the Worth Dot test to find a preliminary prism amount. Double vision, eye strain, blurred vision, fatigue, headache, dizziness and pain around the eye are common signs and symptoms between the two conditions. Tranaglyphs are similar to vectograms, however instead of there being two different transparent image cards that need to be fused into one, there is one image card with a stereo image already pre-made onto the card. Patel SH, Cunnane ME, Juliano AF, Vangel MG, Kazlas MA, Moonis G. Imaging appearance of the lateral rectus-superior rectus band in 100 consecutive patients without strabismus. It is very a common condition where there is a comitant exotropia greater at near than at distance by at least 10 prism diopters. Using magnetic resonance imaging (MRI), a coronal image 6 mm anterior to the eyeball-optic nerve junction was measured and used to examine the extraocular muscle (EOM) path shift . A recent review in January 2020 supported the evidence that when the symptoms of diplopia are burdensome to the patient, surgery is the only treatment that can eliminate the misalignment almost 100%. Repka MX and Eric Downing E. Characteristics and surgical results in patients with age-related divergence insufficiency esotropia. What is convergence spasm? However, the cause of convergence insufficiency is often unknown. Patients with convergence insufficiency will often complain of eye strain when looking at near objects (reading, writing, computer work, etc. Adjustable small-incision selective tenotomy and plication for correction of incomitant vertical strabismus and torsion. DIVERGENCE INSUFFICIENCY - Optography 2016. [5], In recent imaging studies, Patel et al. CHNuclear and infranuclear ocular motility disorders. Divergence Insufficiency: An Ongoing Challenge - Review of Ophthalmology Head trauma 3. With a trial frame, she was not able to appreciate RDS stereoacuity in-office. Although ophthalmoplegia associated with temporal arteritis has been rarely attributed to brainstem23 or ocular motor nerve injury,24 most cases are thought to result from extraocular muscle ischemia.25,26 The association of divergence insufficiency and temporal arteritis in these 2 cases emphasizes that the diagnostic signs of this ocular motor disturbance are not localizing and could occur in other disorders associated with local injury of extraocular muscles, such as myasthenia gravis, as was identified in 1 of the patients of Lepore.15, Divergence insufficiency was observed in 4 patients with pseudotumor cerebri. The EOM angles in these patients ranged from 100 to . 133. Connective tissues reflect different mechanisms of strabismus over the life span. The additional literature on the subject of divergence insufficiency largely consists of small series of patients mainly reported in the precomputed tomography (CT) era and patients with neurologically isolated divergence insufficiency mixed with those who additionally had other signs of intracranial hypertension or a structural brain lesion.15,18-21 The purpose of my study was to describe a large series of patients with divergence insufficiency evaluated in the post-CT era to determine the natural history of neurologically isolated cases, to determine the spectrum of neurologic associations, and to identify clinical features that might be helpful in distinguishing those patients with an isolated disorder from those harboring neurologic disorders. With CI, the eyes do not point together inward as one looks at objects close-up. Accessibility Statement, Our website uses cookies to enhance your experience. 5. It is reasonable to initially defer further investigation, including neuroimaging, in patients who have no other neurologic symptoms or signs. The SR was chosen when hypertropia was greatest in sursumversion or absent in infraversion. Unfortunately, since the ocular ductions appear full in a patient with suspected divergence insufficiency, objective means to assess the state of ocular comitancy do not exist for office determination. Primary divergence insufficiency is generally a benign condition. This means the eyes do not like to move inward toward the nose and is problematic when trying to look at a near target. The author has no commercial or proprietary interest in any product or company mentioned in this manuscript, and has no financial interest nor receives payment as a consultant, reviewer, or evaluator. Histories reveal the possibility of a number of etiologic factors. All rights reserved. Privacy Policy| Typically, patients note that they do not have any diplopia at near. There are many different ways to do this, but the best method to use depends on the type of binocular vision disorder for which you are prescribing. DRHartnett 9. LMDivergence paralysis with increased intracranial pressure: further observations. 130. J AAPOS 2014;18:370-373. The clinical neurologic evaluation is a powerful tool that distinguishes those with a primary disorder from those harboring an underlying neurologic or systemic condition. PDF Divergence Insufficiency - Jama People notice symptoms while reading or doing other near work. These questions are archived at https://neuro-ophthalmology.stanford.eduFollow https://twitter.com/NeuroOphthQandA to be notified of new neuro-ophthalmology questions of the week.Please send feedback, questions, and corrections to tcooper@stanford.edu. She had been previously diagnosed with esotropia and amblyopia but was not currently wearing any correction. Any patient presenting with divergence insufficiency and neurological symptoms should undergo a full neurological evaluation and imaging.2, Vision therapy aims to decrease symptoms of vergence anomalies by increasing the compensating fusional vergence range (base-in for esophoria and base-out for exophoria). 2013;251:16411644. It involves a specialty optical system and a uniquely created image book. Retrospective case reviews of patients with an acquired hyper deviation secondary to a superior oblique palsy found that 76% to 92% of participants were successfully treated with prism alone.5,6. Temporal GVRT was chosen for the IR and nasal GVRT for the SR. FDDutton divergence excess eyewikibc kutaisi vs energy invest rustavi. The other patient with focal brainstem injury, a stroke with double vision, vertigo, and left arm numbness, did not have the responsible lesion identified by the CT. Weird vision divergence upon waking at night - Retirement -Social Jacobson DM. The tool itself can be calibrated to work on increasing divergence or convergence, depending on what it is set to. DBGlaser JAInman In a Tranaglyph, the amount of convergence or divergence needed to fuse the image is pre-determined, i.e. an electromyographic study. Her medical history was unremarkable, and her ocular history was remarkable only for low myopia, for which she wore glasses. To increase convergence, the two cards will be pushed inward, making the image smaller (Small In for the SI in SILO). The clinical neurologic evaluation is a powerful tool that distinguishes those with a primary disorder from those harboring an underlying neurologic or systemic condition. The opposite of divergence insufficiency is divergence excess. Bothun ED, Archer SM. Many affected patients experience spontaneous resolution of double vision within several months. Therapy will aim at increasing negative fusional vergence ranges to strengthen the fusional vergence system and. Between the polarizing glasses and the patients fusional vergence system, he or she will be asked to either converge or diverge to fuse the two partial images into one 3-D image. In some circumstances, individuals with divergence insufficiency will also suffer from high esophoria or esotropia, meaning the eyes like to sit in an inward position. 128. What causes divergence insufficiency? I still have mild double vision and . Prism prescriptions often greatly improve the quality of life of your patients by reducing asthenopia and diplopia. In fact, when the vergence system is struggling, the accommodative system often picks up the slack and becomes overworked, which can also play a role in some of the symptoms of eye strain, fatigue, and headaches. Reproduction in whole or in part without permission is prohibited. Symptoms resolved in 8 (40%) of 20 patients after a median of 5 months. p.p1 {margin: 0.0px 0.0px 0.0px 0.0px; line-height: 12.0px; font: 10.0px Sabon} p.p2 {margin: 0.0px 0.0px 0.0px 0.0px; text-indent: 10.0px; line-height: 12.0px; font: 10.0px Sabon} p.p3 {margin: 0.0px 0.0px 0.0px 0.0px; line-height: 12.0px; font: 12.0px 'Helvetica Neue'; color: #867245; min-height: 12.0px} p.p4 {margin: 0.0px 0.0px 0.0px 0.0px; line-height: 12.0px; font: 12.0px 'Helvetica Neue'; color: #b87c4c} p.p5 {margin: 0.0px 0.0px 0.0px 0.0px; line-height: 12.0px; font: 12.0px 'Helvetica Neue'; color: #b37749} span.s1 {letter-spacing: -0.2px}. [13]In their case series patients with lateral incomitance, the adjustable suture was generally placed on the MR opposite the horizontal direction of the greatest ET. PDF CLINICAL SCIENCES Divergence Insufficiency Revisited - JAMA Ductions should be tested with the fellow eye covered. A similar technique is used for rehabilitation: the patient is instructed to do push-up exercises (looking at an object intermittently moved in and out from the bridge of the nose) daily at home to decrease the near point of convergence.Divergence InsufficiencyDivergence insufficiency is characterized as follows: Comitant esotropia is present at distance but not at near. Ductions and versions are full. It is most often related to raised intracranial pressure or Chiari malformation.Classic causes of divergence insufficiency include the following: Raised intracranial pressure Chiari malformation Head trauma Intracranial hypotension (low CSF pressure syndrome) Cerebellar lesions Midbrain massAbnormal Horizontal Conjugate DeviationsGaze deviations are relatively common in large cerebral and pontine lesions (Fig. Convergence Insufficiency (CI): Symptoms, Diagnosis - Cleveland Clinic characterized by a turning inwards or outwards from the nose thus preventing parallel vision: caused by paralysis of an eye muscle, etc . In the remaining 17 patients who were still alive, the total duration of follow-up extended from 1 month to 16 years (median, 35 months). The signs and symptoms with this condition are similar to convergence excess. Long-term follow-up and clinical features of the 2 groups were compared. Wednesday, March 15, 2023 | All Eyes On Evaporation, Thursday, April 13, 2023 | All Eyes On Evaporation, Tuesday, April 18, 2023 | All Eyes On Evaporation. the accommodative and vergence systems are tightly correlated. Cunningham Peripheral double pictures Usually double vision arises from a squint deviation of the eyes and is checked with a torch and a red glass before one eye to separate the pictures. RDInternuclear ophthalmoplegia in giant cell arteritis. 3. SDiagnosis and management of divergence weakness in adults. When prescribing ground-in prism, high index lenses, plastic frames and frames that are smaller in size help improve the weight and cosmesis of the lenses. Heavy Eye vs. unable to diverge appropriately to a given target. DSDiagnosis of Central Disorders of Ocular Motility: The Neurology of Eye Movements. Patients who wear contact lenses the majority of the time or who have undergone refractive, cataract or strabismus surgery may not be happy with the idea of moving or going back to spectacle wear even if it relieves asthenopia or diplopia. Although no unsuspected neurologic disorder surfaced during the period of follow-up in these patients, I strongly recommend that a patient with isolated divergence insufficiency be followed closely to detect, for example, signs of developing intracranial hypertension or abducens nerve palsy. Questions: 125. 2000;118(9):12371241. Therapists can make this activity more advanced by increasing the amount the, changing the target) or by using multiple, and making the patient look from one to another, , however instead of there being two different transparent image, that need to be fused into one, there is one image. Copyright 2023 Jobson Medical Information LLC unless otherwise noted. The use of MRI imaging is confirmatory rather than "required" to make the diagnosis, since diagnosis is mainly clinical. will be pushed inward, making the image smaller, will be pulled outward, making the image larger, Increasing or decreasing the distance between the two. From there, basic vergence exercises will be added in. 1978;76:610-53. 133. The Apt Lecture. In many of these cases, the initial management strategy is prescribing vertical prism.1 Often, if the vertical deviation is decreased or eliminated, the patient may be able to comfortably fuse the horizontal deviation. My practice represents a balance of primary care and referral-based consultative neuro-ophthalmology. 3 Advanced Exercises for Convergence and Divergence Insufficiency doi:10.1001/archopht.118.9.1237. Divergence insufficiency: characteristics, diagnosis, and treatment The patient with a metastatic lesion of the midbrain additionally had skew deviation, an afferent pupillary defect without visual loss, and other signs of brainstem injury, but no symptoms or signs of intracranial hypertension. Chang MY et al. Diplopia Developed in Later Life, An Ophthalmologic Approach GBTobin Questions with answers: 125. The global layer of each rectus EOM, passes through the pulley and becomes contiguous with the tendon to insert on the globe. Of the 15 patients with secondary divergence insufficiency, an underlying neurologic or systemic disorder was either known or initially suspected in all based on the initial history and physical examination. Audio blog post. [12]Later Chaudhuri and Demer reported 24 patients and compared the results of those undergoing lateral rectus resection (n = 8) to those undergoing medial rectus recession (n = 16). Symptoms resolved in 8 (40%) of 20 patients after a median of 5 months. [5] In addition, patients may have had eyelid surgery, face lifting,[6] or even apparently uncomplicated refractive or cataract surgery.[6][8]. In many individuals with vergence problems, accommodation will be worked on first to ensure it is equal between the two eyes. J Pediatr Ophthalmol Strabismus. Once this can be repeated multiple times, the amount of required divergence or convergence can be increased, thus expanding the vergence range and strengthening the problem area. PCBurian This patient continued with vision therapy to help improve her sensory and motor fusion with the hope of eventually titrating down the amount of prism she wears. A stereoscope is a tool used to help expand fusional vergence ranges once a baseline has been established. In the 17 patients with primary divergence insufficiency who had adequate information to ascertain long-term follow-up, double vision persisted in 9 individuals. Simultaneous injury of the medial longitudinal fasciculus has been postulated as another reason sixth cranial nerve palsy may appear comitant.4 However, none of the patients classified as primary had clinical signs of internuclear ophthalmoplegia. Terms of Use| [1]SES should be differentiated from heavy eye syndrome (HES) which is an association of axial high myopia, esotropia, and hypotropia. How to test convergence eyes | Math Index Bender 2016;28(1):38-42. Although each method has its advantages and disadvantages, they all suffer from being subjective. 128. Of the 15 patients with secondary divergence insufficiency, there were 11 women and 4 men, ranging in age from 8 to 86 years, with a median (mean) age of 56 (51) years. 2012;95(2):192-7. Br J Ophthalmol. Patients were categorized into 2 groups, primary (ie, neurologically isolated based on clinical criteria) and secondary (ie, associated with a neurologic or systemic disorder). 2012. However, they had a recurrence rate of almost 7% over their mean follow-up period of 39 months. . For example, many investigators propose criteria to differentiate divergence insufficiency from divergence paralysis or paresis.1-3 However these arbitrarily defined criteria more likely describe varying severity of symptoms and ocular motor signs along a continuum of the same condition. changing the target) or by using multiple vectograms and making the patient look from one to another and quickly adapting the vergence system appropriately to each target (this is called jumping vectograms). Pang Y, Teitelbaum B, Krall J. "The term divergence insufficiency implies a problem at the level of the brainstem, suggesting that there is decreased neural output to the extraocular muscles," said Prem S. Subramanian, MD, PhD, at the University of Colorado in Aurora. In high-myopia patients without double vision, the ocular axis length was 27.6 1.3 mm. 12. Patients with 20 to 30 PDs of exotropia should be left with 10 to 15 PDs of residual vergence demand, and patients with a vertical strabismus of 3 to 10 PDs should be left with 2 to 4 PDs of residual vergence demand.7 RVD is best used in patients who have vergence ranges that have been maximally trained through vision therapy but still need prism to maintain binocular vision in free space.12. DOI: Demer JL. Customize your JAMA Network experience by selecting one or more topics from the list below. Accepted for publication February 11, 2000. Therefore, it forces the patient to use both eyes properly to see the image. Strabismus. Strabismus, or hypertropia, is a condition when one or both of the eyes are not properly aligned. Adnexal signs such as: retraction of the upper eyelid into the superior orbit (superior sulcus deepening), aponeurotic blepharoptosis, floppy lower lids, and high upper eyelid crease. More advanced exercises for vergence insufficiencies include Vectograms, Tranaglyphs, and Stereoscopes. A recent review in January 2020 supported the evidence that when the symptoms of diplopia are burdensome to the patient, surgery is the only treatment that can eliminate the . To begin therapy, many therapists will focus first on normalizing the accommodative system. If the patient gives a fusion response with or without prism but movement on the unilateral cover test is seen, then anomalous correspondence is suspected and relieving or corrective prism is not an appropriate management option. It can also decrease distance judgement, coordination, and sports performance. Sagging Eye Syndrome: Connective Tissue Involution as a Cause of Horizontal and Vertical Strabismus in Older Patients. 13. Convergence insufficiency (CI) is a vision disorder. If hypertropia persisted, further 5%10% increments of GVRT up to a maximum of 90% were added with monitoring of alignment. How is convergence insufficiency treated? Sometimes it is exacerbated by fatigue and improves with rest. Therapy will aim at increasing negative fusional vergence ranges to strengthen the fusional vergence system and help make average daily distance tasks more manageable with less frequent symptoms. Each patient was classified into 1 of 2 categories of divergence insufficiency based on results of the general neurologic assessment at their initial evaluation. Godts D, Mathysen DG. The main treatment for convergence insufficiency is vision therapy. There were 20 patients classified as having primary and 15 patients classified as having secondary divergence insufficiency. Divergence insufficiency is the opposite problem of convergence insufficiency. Vision therapy uses various exercises to train the connection between the eyes and the brain as more than 50% of the brain is dedicated to visual function. Ductions and versions are full. This means the eyes do not like to move outward toward the ears and is problematic when trying to view a distant target. With one eye covered, the patient is able to move the open eye laterally and the pupil will dilate. Bergman, Pugh and Duke-Elder favored the view of divergence as a passive result of relaxation of convergence. MGeorge Biousse V and Newman NJ. In those patients without an established disorder, additional clinical clues indicated the need for neuroimaging or additional diagnostic studies, independent of the signs of divergence insufficiency. While viewing the Worth Dot test, prism is gradually increased until the patient reports fusion. The eyes deviate horizontally toward a cortical lesion, the eyes deviate horizontally away from a cortical seizure focus, and the eyes deviate horizontally away from a pontine lesion. 8 (89%) had successful with postoperative vertical alignment and 4 (50%) were successfully corrected, with <5 of cyclotorsion postoperatively. DJDivergence insufficiency. Relieving prism is often prescribed for patients with intermittent strabismus and sometimes for those with constant strabismus. Primary and secondary forms exist, with the latter more urgently addressed due to neurologic comorbidities. Classic causes of divergence insufficiency include the following: Raised intracranial pressure Chiari malformation American Journal of Ophthalmology, Volume 209, January 2020, Pages 55-61. Although younger patients may not be able to give good, subjective feedback, older children and adult patients should wear the trial prism set while engaging in an activity that normally causes them to experience diplopia or asthenopia (reading or distance viewing) to see if it eliminates diplopia and improves comfort. Although small amounts of vertical prism can be prescribed in contact lenses, patients who need prism usually have to wear it on a spectacle lens.
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